NeuroScience TravaGen 120 Capsules

NeuroScience TravaGen 120 Capsules

NeuroScience

$64.00
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SKU:
NS0018
UPC:
659468101134
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New
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These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
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Contains a blend of ingredients important for mood and reducing stress*
Utilizes L-tryptophan to provide gentler conversion to serotonin compared to 5-HTP*

Key ingredients
L-tryptophan: An essential amino acid and precursor to serotonin and melatonin. L-tryptophan provides gentler conversion to serotonin compared to 5-hydroxytryptophan (5-HTP) as the rate-limiting step in the synthesis of serotonin is the conversion of L-tryptophan to 5-HTP (1). Serotonin is important for regulating mood and sleep-wake function (2).

Taurine: Neuroprotective amino acid that provides antioxidant protection and demonstrates GABA-A agonist activity (3-5).* GABA is the primary inhibitory neurotransmitter in the brain important for calm and sleep (6-8).

L-theanine: Amino acid that acts as a glutamate receptor antagonist (9).* Glutamatergic signaling plays a role in underlying mechanisms related to anxiousness and stress (10). In a randomized, double-blind, placebo-controlled study, L-theanine was shown to significantly reduce stress (11).*

Vitamins B and C: Active forms of vitamin B6, folate, B12, and C are important for serotonin synthesis (12-16).*

References

  1. Birdsall T. Altern Med Rev. 1988;3(4):271-80.
  2. Monti J. Sleep Med Rev. 2011;15(4):269-81.
  3. Kumari N, et al. Adv Exp Med Biol. 2013;775:19-27.
  4. Shimada K, et al. Adv Exp Med Biol. 2015;803:581-96.
  5. Kletke O, et al. PLoS One. 2013;8(4):e61733.
  6. Gou Z, et al. Dongwuxue Yanjiu. 2012;33(E5-6):E75-81.
  7. Mohler H. Neuropharmacology. 2012;62(1):42-53.
  8. Saper C, et al. Nature. 2005;437(7063):1257-63.
  9. Kakuda T, et al. Biosci Biotechnol Biochem. 2002;66(12):2683-2686.
  10. Bermudo-Soriano C, et al. Pharmacol Biochem Behav. 2012;100(4):752-74.
  11. Kimura K, et al. Biol Psychol. 2007; 74(1):39-45.
  12. Dakshinamurti K, et al. Ann N Y Acad Sci. 1990;585:128-44.
  13. Bottiglieri T. Psychiatr Clin North Am. 2013;36(1):1-13.
  14. Stahl S. J Clin Psychiatry. 2008;69(9):1352-3.
  15. Antoniades C, et al. Circulation. 2006;114(11):1193-201.
  16. May J, et al. Brain Res Bull. 2013;90:35-42.
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